5 to 140 x 10(-5) Pa-0.5 under a 400 V/mm dc field. The largest figure of merit of 200 x 10(-5) Pa-0.5, which is about 8 times higher than that of conventional phase transition materials barium strontium titanate (BST), was obtained in PLBZST ceramics with 6 wt. % excess PbO when a 600 V/mm dc bias field was applied. Therefore, improvement of SYN-117 in vitro pyroelectric property is beneficial for the development of infrared detectors. (C) 2011 American Institute of Physics. [doi:10.1063/1.3596577]“
“Anaphase-promoting complex/cyclosome (APC/C) is a key E3 ubiquitin ligase in cell division, which catalyses ubiquitination of cell-cycle
regulators. Studying this complex could reveal important information regarding its application in selleck chemicals cancer research and therapy. In this study, 4 synthesized small interfering RNAs (siRNAs) were transfected into HEK293T cells to suppress messenger RNA (mRNA) of Apc11; 2 of these reduced the amount of Apc11 mRNA by over 50%. Further experiments showed that rather than causing apoptosis, siRNA transfection led to cell-cycle distributions characterized by less time spent in G2/M phase and more time spent in G1 phase. This phenomenon was specifically induced by Apc11 silencing, as co-transfection of
siRNA and an Apc11 plasmid could reverse this distribution bias. Our results suggested that siRNA targeted against Apc11 could hamper entry into G2/M phase. Current efforts are focused on elucidating the Crenolanib function and utility of the APC complex for clinical applications.”
“The effects of misfit strain on the electrocaloric (EC) properties of BaTiO3 thin films arestudied by using the Landau-Devonshire thermodynamic theory. The “”misfit-strain temperature”"
phase diagrams for different electric fields are constructed. It was found that the EC effect of a BaTiO3 thin film is strongly dependent on misfit strain. More interestingly, we found that BaTiO3 thin films with tensile misfit strain exhibit a sizable EC effect in a wider temperature range in comparison with those with compressive misfit strain. (C) 2011 American Institute of Physics. [doi:10.1063/1.3596814]“
“The increased interest in the biological activities of the leaves of Mucuna utilis necessitated this study which evaluated the chemical composition, especially the presence of antiphysiological and toxic factors in the leaves. The results of the phytochemical analyses were: alkaloid, 9.60 +/- 0.141%; flavonoids, 4.90 +/- 0.20%; saponins, 24.60 +/- 1.979%; tannins, 32.55 +/- 0.778% and cyanoglycosides 20.736 +/- 0.91%. The results showed crude protein to be 31.91 +/- 2.60%; carbohydrate, 53.65 +/- 2.11%; crude fibre 14.80 +/- 0.42%; moisture, 11.37 +/- 0.632%; ash, 0.11 +/- 0.01% and crude fat, 2.97 +/- 0.009. The results also showed appreciable presence of macro and micro-elements, while the ascorbic acid and vitamin A contents were 25.36 +/- 0.212 and 9.83 +/- 0.15 mg/100 g respectively. These results showed that the leaves of M.