The type of PS was diagnosed using the 2D echocardiography and the severity was measured using the Doppler echocardiographic measurement assessed by modified Bernoulli equation. Echocardiography datas were collected from ramdomized results, using our center modality, Philips IE 33 (Philips Andover, Andover, MA, USA), GE vivid E9 (GE Healthcare, Fairfield, Inhibitors,research,lifescience,medical CT, USA), The Siemens

Acuson sequoia 512 (Siemens Germany, North Rhine-Westphalia, Germany). Parasternal short axis view is mainly used for evaluation of PS, and additional view was performed, when it was nessacery. The peak-to-peak pressure gradient difference between the RV and the PA was measured, as well as the mean transpulmonic pressure gradient. When the gradient on echocardiography was greater than 40 mmHg, or the estimated right ventricular pressure was greater than 50 mmHg, patients who have exertional dyspnea, angina, syncope, or presyncope and RV-PA peak-to-peak gradient greater than 30 mmHg at catheterization,

BPV was Inhibitors,research,lifescience,medical indicated.9),10) During the transcatheter procedure, the pre-procedural measurement between the RV and PA was measured and the post-procedural Inhibitors,research,lifescience,medical measurement was also measured, to decide the success of the procedure. We considered the procedure Ku-0059436 in vitro successful when the pressure gradient was less than 20 mmHg. Follow-up echocardiography was performed within 24 hours of the procedure, 1 week, 3 months, 6 months, and yearly thereafter. Parametric data were entered into a Microsoft Excel 2007 spreadsheet (Microsoft, Redmond, WA, USA). Results

are presented as mean ± standard deviation or numbers and percentages Inhibitors,research,lifescience,medical Inhibitors,research,lifescience,medical and analyzed using MedCalc ver 12.3.0.0 (MedCalc Software, Ostend, Belgium). Results Subjects The mean age of the patients were 38.35 months (± 48.55 months) and they ranged from 1 month to 192 months (16 years old), the median age was 17 months. Of the 112 total patients, there were 46 male patients (41.07%) almost and 66 female patients (58.92%). Patients with concomitant simple observable heart diseases consisted of 32 patients. They were 29 atrial septal defect patients (25.9%), 2 ventricluar septal defect patients (1.8%), 3 patent ductus arteriosus patients (2.7%) and 3 patent foramen ovale patients (2.7%). The mean follow-up duration of the patient was 30.64 months (± 26.84 months) ranging from 3 months to 108 months (median, 24 months) (Table 1). Table 1 The clinical data of patients with pulmonary valve stenosis Adverse events There were no noted major complications. Two cases (1.79%) of minor complications were detected, both of which were spiking fever, but both subsided after a day (Table 1). Echocardiographic data The type of diagnosed PS were 85 valvular PS (75.