001, P = .036, P < .001, and P = .002, respectively),compared with the contralateral side. There were also significant differences in FA (P < .001), mean diffusivity (P = .008), lambda(2) (P < .001), and lambda(3) (P = .001) of the deep white matter tracts projecting to or from the MR imaging visible FCD compared with the contralateral side.

Conclusion: With use of MEG dipole clusters to localize the epileptogenic zone, diffusion-tensor imaging can help identify alterations in tissue microstructure beyond

the MR imaging visible FCD. (c) RSNA, 2009″
“Azithromycin dihydrate is a semi-synthetic macrolide antibiotic drug, effective against a wide variety of bacteria. It is primarily used to treat the bacterial infections associated with weaker immune system. A simple, accurate, rapid and cost effective spectrometric method for the estimation of azithromycin has been developed and validated by the acidic hydrolysis of the drug with sulphuric acid and monitoring buy CP-690550 the absorbance at 482nm. The validated

method was successfully applied for dissolution studies of azithromycin dihydrate tablets. The developed method was validated as per ICH Q2 (R1) guidelines, which include linearity, precision, accuracy, specificity, robustness, detection and quantitation limits. The method has shown good linearity over the range of 10.0 to 50.0 mu g/mL with a correlation coefficient of 0.9995. The percentage recovery of 99.98 % showed that the method was highly accurate. The precision demonstrated relative standard deviation of less than 2.5 %. The specificity of the method was proven as the excipients JAK inhibitor present in the tablets did not interfere with the assay. The developed and validated method was successfully applied for dissolution

studies with a cumulative release of 99.3 % in 45 minutes. The proposed Selleck C188-9 method might be applied in routine quality control in the pharmaceutical industries as it has shown very good precision, accuracy and simplicity.”
“Electrospinning is a simple method of producing nanofibers by introducing electric field into the polymer solutions. We report an experimental investigation on the influence of processing parameters and solution properties on the structural morphology and average fiber diameter of electrospun poly ethylene oxide (PEO) polymer solution. Experimental trials have been conducted to investigate the effect of solution parameters, such as concentration, molecular weight, addition of polyelectrolyte in PEO solution, solvent effect, as well as governing parameter, such as applied voltage. The concentration of the aqueous PEO solution has shown noteworthy influence on the fiber diameter and structural morphology of electrospun nanofibers. At lower concentrations of PEO polymer solution, the fibers showed irregular morphology with large variations in fiber diameter, whereas at higher concentrations, the nanofibers with regular morphology and on average uniform fiber diameter were obtained.