02 1.93* 1.30–2.88 Poor relation with colleagues 28 1.40* 1.04–1.89 1.61* 1.14–2.26 1.16 0.89–1.53 1.70* 1.17–2.47 Poor relation with supervisor 28 1.71* 1.27–2.31 2.16* 1.53–3.05 1.28 0.98–1.68 1.78* 1.22–2.60 Pe prevalence in study population †Reference category: no productivity loss ‡Reference category: no sick leave * p < 0.05, adjusted for sex, this website age, and ethnicity Table 3 Effects of adjustment for work-related factors, health, and lifestyle-related factors on the association between educational level and productivity loss at work (n = 647)   10–20 % productivity loss† 30 % or more productivity

loss† Low education‡ Intermediate education‡ Low education‡ Intermediate education‡ OR 95 % CI OR 95 % CI OR 95 % CI OR 95 % CI Model 1: sex, age, and ethnicity 1.46* 1.01–2.11 1.22 0.89–1.67 1.49 0.98–2.26

1.28 0.87–1.87 Model 2: model 1 + reduced perceived general health 1.45* 1.00–2.08 1.21 0.88–1.65 1.43 0.94–2.19 1.28 0.87–1.87 Model 3: model 1 + work-related factorsa 1.54* 1.06–2.23 1.24 0.90–1.70 1.54* 1.01–2.35 1.26 0.86–1.85 Model 4: model 1 + lifestyle-related factorsb 1.46* 1.02–2.11 1.22 0.89–1.68 1.50 0.98–2.30 buy Emricasan 1.35 0.92–1.97 Model 5: model 1 + health + work-related factors 1.53* 1.05–2.21 1.23 0.90–1.70 1.49 0.97–2.28 1.27 0.86–1.86 Model 6: model 1 + health + work-related factors + lifestyle-related factors 1.53* 1.06–2.22 1.24 0.90–1.71 1.54* 1.01–2.37 1.32 0.90–1.94 †Reference category: no productivity loss ‡Reference category: high educational level aWork-related factors: low job control, poor relation with colleagues, and poor relation with supervisor bLifestyle-related factors: insufficient vigorous physical activity * p < 0.05 Sick leave As shown in Table 2, individuals

with a low (OR = 1.81, 95 % CI 1.15–2.85) or intermediate educational level (OR = 1.85, 95 % CI 1.21–2.82) were more likely to have 10 or more workdays sick leave. Obesity was statistically significantly Brigatinib order associated with more sick leave days after adjustment for gender, age, and ethnicity (OR = 2.29, 95 % CI 1.27–4.12). The strongest association was found between perceived general health and sick leave (OR = 6.26, 95 % CI 3.47–11.29). Several work-related factors were also associated Rebamipide with sick leave: working in awkward postures, low job control, low skill discretion, and a poor relation with colleagues or supervisor (Table 2). The combination of work-related factors partly explained the association between educational level and sick leave (Table 4). After adjustment for work-related factors, the strength of the association between a low educational level and 10 or more days of sick leave decreased from OR = 1.81 to OR = 1.62 (23 % change). Combined adjustment for work-related factors and perceived general health further reduced the strength of the association between a low educational level and 10 or more days of sick leave with an additional 4 %.