17 vs. 5.23 in the Baby Boomers and 12.11 vs. 12.47 in the non-Baby Boomers, p<0.001). Conclusions In the year following the CDC call, screening rates rose significantly (10%) in the Baby Boomer cohort, but also decreased significantly (10%) in the non-Baby Boomer cohort. Further study is needed to see if these changes were due to healthcare professionals changing their criteria for screening from risk factors to birth cohort. It is of interest that projected rates suggest that screening rates in both cohorts will increase significantly in the second year

following the CDC call to action, which may indicate further changes in screening criteria. Disclosures: Carol Smyth – Employment: Medivo, Inc. Jason Bhan this website – Employment: Medivo Nancy Reau – Advisory Committees or Review Panels: Kadmon, Jannsen, Vertex, Idenix, AbbVie, Jannsen; Grant/Research Support: Vertex, Gilead, Genentech, AbbVie, BMS, Jannsen, BI The following people have nothing to disclose: Tatiana Sorokina, Ajitpal S. Dhaliwal Background and Purpose: In New York City, an estimated 146,500 residents, or 2.4% of the adult population, have chronic HCV infection, and half may be unaware of their infection. In 2013, New York State mandated that primary care providers offer HCV antibody testing to all PLX4032 persons born during 1945-1965

(baby boomers). Many high-risk HCV positive persons medchemexpress are not screened in primary care settings, and, of those who are screened, many do not receive an RNA test to confirm current infection. Check Hep C was designed to integrate HCV testing and linkage to care into community-based

organizations to improve HCV testing rates. Methods: Check Hep C funded 8 organizations at 12 community sites to provide HCV testing and patient navigators in high prevalence neighborhoods. The testing method involved targeted outreach, point of care rapid antibody testing, and, after a positive antibody test, an immediate blood draw for RNA testing. Sites included Federally Qualified Health Centers (FQHC), Syringe Exchange Programs (SEP), and combined FQHC/SEP facilities. A central database collected information including participant demographics, test results, and risk factors. Results: From May 2012 to April 2013, 4,751 individuals were tested. Hispanics comprised 49% of participants, black/non-Hispanic 40%, and white/non-Hispanic 9%. Fifteen percent of participants were homeless at the time of testing, and 50% had a history of incarceration. Ever having injected drugs was reported by 1128 (25%) participants, 361 of whom (33%) reported use in the past 30 days. A total of 880 (19%) were HCV antibody positive. Of 678 antibody positive patients who had an RNA test (77% acceptance rate), 512 (76%) had current infection.