A great deal

of research has been accomplished for see more directing osteoblastic/cementoblastic differentiation and neural differentiation from dental stem cells. To differentiate dental stem cells for use in tissue engineering and regenerative medicine, there needs to be efficient in vitro differentiation toward the osteoblastic/cementoblastic and neural lineage with well-defined and proficient protocols. This would reduce the likelihood of spontaneous differentiation into divergent lineages and increase the available cell source. This review focuses on the multilineage differentiation capacity, especially into osteoblastic/cementoblastic lineage and neural lineages, of dental stem cells such as dental pulp stem cells (DPSC), dental follicle stem cells (DFSC), periodontal ligament stem cells (PDLSC), and dental papilla stem cells (DPPSC). It also covers various experimental strategies that could be used to direct lineage-specific differentiation, and their potential applications in tissue engineering and regenerative medicine.”
“There is substantial evidence that omega-3 polyunsaturated fatty acids (PUFAs) have therapeutic potential in neurology and psychiatry. Spinal cord injury (SCI) and traumatic brain injury (TBI) have dramatic consequences, and no neuroprotective or neuroregenerative treatment is available. The pathogenetic mechanisms involved in SCI and TBI include excitotoxicity

associated with increased glutamate, Selleck Mocetinostat oxidative stress and neuroinflammation. Studies have shown that omega-3 PUFAs can MEK inhibitor side effects induce significant neuroprotection in SCI. In rat hemisection and compression SCI, long-chain omega-3 PUFAs such as docosahexaenoic acid, administered within the first hour after injury, can reduce neuronal and glial cell death, limit oxidative stress and the inflammatory cascade triggered by the primary injury, and improve neurological function. Emerging

observations in TBI support a similar neuroprotective potential. Omega-3 PUFAs also have neurotrophic properties. These findings support the idea that treatment with omega-3 PUFAs could represent a promising therapeutic approach in the management of neurotrauma, which would be easy to translate to the clinic, considering the well-documented safety and tolerability of these compounds in other indications.”
“We analyze the near-band-edge photoluminescence of electrochemically deposited ZnO nanowires and directly correlate the photoluminescence properties with the carrier concentration in the nanowires as determined from electrochemical impedance spectroscopy. We find a donor density of 8×10(19) cm(-3) in the as-deposited nanowires and show that the near-band-edge emission results from band-to-band recombination processes (delocalized states). A photoluminescence band centered at 3.328 eV scales with the diameter of the nanowires and is assigned to recombination processes involving surface states.