Biomarker upregulation had no prognostic value for biochemical re

Biomarker upregulation had no prognostic value for biochemical recurrence after radical prostatectomy, even after considering pathological stage, whole tumour Gleason grade and preoperative serum PSA level.”
“The Cu2O nanoparticles having average crystallite diameters similar to 8-16 nm were synthesized by a simple solvothermal method. The Mn was doped in the Cu2O sample of crystallite

size similar to 8 nm. The effects of the size and doping concentration on the crystal structures of the nanoparticles were investigated. The x-ray photoelectron spectroscopy studies clearly showed that the Mn was incorporated into the Cu2O lattice as Mn2+ due to the substitution of the Cu+ ions by Mn2+ ions. selleck screening library The quantum confinement effects were observed in the nanoparticles. The multiple emissions from the Cu2O

were quenched in the Mn doped nanoparticles and only blue light emitting Cu2O nanoparticles were obtained due to the transition T-4(2)->(6)A(1) of Mn. The effects of the doping concentration and the particle size on the relaxations dynamics of the Cu2O nanoparticles were mainly investigated using photoluminescence decay.”
“From a 1-BuOH-soluble fraction of an extract of the leaves of Elaeocarpus japonicus, six megastigmane glucosides (1-6) were isolated. Five were known compounds (2-6), LB-100 i.e. amelopsisionoside, citroside A, roseoside, alangionoside A and turpinionoside AZD9291 A, respectively. The structure of the new compound, named elaeocarpionoside, was elucidated to be (3R,4R,5S,6S,7E,9R)-megastigman-7-ene-3,4,9-triol 9-O-beta-d-glucopyranoside by spectroscopic analyses and the

modified Mosher’s method.”
“Background: The objectives of this cross-sectional, observational study were to determine the prevalence of self-reported headache among the employees of the large Swiss university hospital, to measure the impact of headache using the MIDAS questionnaire, to assess current treatment and to estimate economic burden of headache considering indirect costs.

Methods: A self-administered questionnaire was distributed internally to 2000 randomly selected employees of the University Hospital Zurich.

Results: 1210 employees (60.5%) responded. Of the 1192 (98.5%) employees who provided sufficiently complete information, 723 (61%) reported at least one headache type in the last three months. The prevalence of migraine, and tension-type headache was 20% and 50%, respectively. Regarding the occupational groups, there was a trend that healthcare staff, administration employees, and medical technicians suffered more from headaches than physicians, correcting for age and sex. The economic consequences of lost productivity were calculated to amount to approximately 14 million Swiss Francs (9.5 million EUR), representing 3.2% of the overall annual expenditure of the hospital for personnel.

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