(C) 2009 European Crohn’s and Colitis Organisation. Published by Elsevier B.V. All rights reserved.”
“BACKGROUND: Screening for dyslipidemia poses some challenges. Nonfasting lipid profiles frequently have elevated triglycerides. In addition, in the standard lipid profile, low-density lipoprotein (LDL) cholesterol is a calculated value rather than a direct measurement and is triglyceride dependent. Non-high-density lipoprotein cholesterol (non-HDL-C) is an alternative method to assess for dyslipidemia and
provides a single estimate of all atherogenic apolipoprotein B-containing lipoproteins.
OBJECTIVE: JQEZ5 manufacturer To calculate the non-HDL-C in adolescents with diabetes and to evaluate risk factors associated selleck inhibitor with an elevated non-HDL-C and to compare the prevalence of dyslipidemia, defined by non-HDL-C, with the prevalence of dyslipidemia defined by LDL cholesterol in the SEARCH study.
METHODS: Data were collected from 502 adolescent patients with diabetes and analyzed. Non-HDL-C was
calculated and levels were categorized into normal, borderline, and high based on the National Cholesterol Education Program.
RESULTS: Lipid profile was performed in 370 patients, 92% of whom had type 1 diabetes. In the 339 subjects with type 1 diabetes, mean hemoglobin A1c (HbA1c) of those with normal non-HDL-C (8.6%) was significantly lower than the HbA1c of those with high non-HDL-C (9.6%) (P=.005). Subjects with normal non-HDL-C had a lower body mass index (BMI) z-score (0.4 +/- 0.8) than the group with borderline and high non-HDL-C (0.75 +/- 0.9%), P = .002. In the 31 subjects with type 2 diabetes, the mean HbA1c of those with normal non-HDL-C (8.1%) and those with borderline non-HDL-C learn more (7.0%) was significantly lower than the mean HbA1c of those with high non-HDL-C (11.8%) (P=.04, and P=.009, respectively). In
addition, the subjects with normal non-HDL-C had a lower BMI z-score (1.3 +/- 1.3) than the group with borderline and high non-HDL-C (2.2 +/- 0.6%), P = .03. The prevalence of dyslipidemia using non-HDL-C was similar to prevalence rates using LDL-C in the SEARCH study.
CONCLUSIONS: In adolescents with diabetes, non-HDL-C is increased with poorer diabetes control and higher BMI. It appears to be a superior nonfasting lipid screening test for adolescents with diabetes that can be readily calculated on a randomly obtained rather than fasting sample. (C) 2014 National Lipid Association. All rights reserved.”
“Operative decompression is indicated for progressive neurological deterioration in patients with cervical compressive myelopathy (CCM). However, the best timing to ensure clinical recovery has not been determined because of the lack of a suitable method. 10 s step (“”step”") test is an easily performed physical test to assess the severity of CCM, particularly for the severity of lower limb dysfunction.