Conclusions Our findings were that in RCCs there is immunoexpression of myosin VI in cytoplasm and nucleus, and cytoplasmic myosin VI is an independent prognostic factor in RCC-specific survival. In the future, myosin VI may have use as a prognostic marker of RCCs. Cytoplasmic myosin VI immunopositivity and nuclear beta-catenin immunostaining were associated with lower Fuhrman grades but not stages. Nuclear myosin VI and beta-catenin immunoexpression are associated with each other. Nuclear E-cadherin and beta-catenin immunostaining
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