Int J Hyperthermia 2006, 22:117–134.PubMedCrossRef 21. Kobelt D, Aumann J, Fichtner I, Stein U, Schlag PM, Walther W: Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression. Mol Biotechnol 2010, 46:197–205.PubMedCrossRef 22. Pshenichkin S, Surin A, Surina E, Klauzińska
M, Grajkowska E, Luchenko V, Dolińska M, Wroblewska B, Wroblewski JT: Heat shock VS-4718 mouse enhances CMV-IE promoter-driven metabotropic glutamate receptor expression and toxicity in transfected cells. Neuropharmacology 2011, 60:1292–1300.PubMedCrossRef 23. Geelen JL, Boom R, buy Autophagy inhibitor Klaver GP, Minnaar RP, Feltkamp MC, van Milligen FJ, Sol CJ, van der Noordaa J: Transcriptional activation of the major immediate early transcription unit of human cytomegalovirus by heat-shock, arsenite and protein synthesis inhibitors. J Gen Virol 1987, 68:2925–2931.PubMedCrossRef Competing interests All authors declared no any conflict of interest. Authors’ contribution FW: Conduct experiments, prepare manuscript HW: perform experiment, data analysis JZ: perform experiments XC: cell culture
CL: experiment design, manuscript revision QH: experiment design, final approval of manuscript. All authors read and approved the final manuscript.”
“Background “”“If you have knowledge, let others light their candles with it””" “”Winston Churchill”" “”“The key question is whether there are new opportunities and new models OICR-9429 for scholarly publishing that would better serve researchers and better communicate and disseminate research findings” * “” “”*Digital broadband Content: Scientific Publishing, OECD, Paris. Available from: “” http://www.oecd.org/internet/interneteconomy/35393145.pdf Open access (OA) paradigm has unquestionably reshaped the traditional
system of scholarly communication by closely linking the concepts of free access to research literature and its easy diffusion and re-use Oxymatrine through massive exploitation of Internet and related technologies and an innovative management of copyright rules. OA journals based on an “author-pays” business model are one of the two routes of the open access paradigm, the so called “gold” route. Golden OA is complementary to “green” OA, founded on depositing accepted manuscripts in institutional or discipline-based repositories. In offering a comprehensive overview of the OA movement, including its history and achievements, Peter Suber defines OA journals as: peer-reviewed journals available online to the reader “”without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself”" [1]. Recent studies of the economic implications of access to journal articles highlight the present and future scenarios of the scholarly publication system [2–5].