The literature review demonstrated that 31% of all cases did not

The literature review demonstrated that 31% of all cases did not have thrombosis of the IJV, however there were only 3/78 (4%) of cases with no associated thrombosis. Therefore thrombosis in the presence of fusobacterial Selleck OICR-9429 bacteraemia would be a more appropriate diagnostic criterion than defining the disease by specific SIS3 price anatomically located thromboses.

In the context of the literature our case was unusual in that it demonstrated unique anatomical variation of the metastases and required surgery as the primary modality of treatment. Our patient did not have any pulmonary metastases which some authors have argued is a key diagnostic criterion for Lemierre’s syndrome [5]. However, our literature review has demonstrated that 30% DZNeP mouse of the cases had no pulmonary involvement. In view of this fact the authors support Riordan’s suggestion that Lemierre’s Syndrome should be reconstituted as fusobacterium necrophorum sepsis, however with the additional diagnostic criterion of the presence of thrombosis. It would seem that the septic metastases are a common complication of the syndrome with huge anatomical variation and as such are not essential to diagnose the condition. Consent Written informed consent was obtained from the patient for publication of this Case report and any accompanying images. A copy of the written consent is available

for review by the Editor-in-Chief of this journal. References 1. Lemierre A: On certain septicemias due to anaerobic organisms. Lancet 1936, 1:701–703.CrossRef 2. Kleinman PK, Flowers RA: Necrotising pneumonia after pharyngitis due to Fusobacterium necrophorum. Paediatr Radiol 1984,14(1):49–51.CrossRef 3. Park D, Rezajooi Glutamate dehydrogenase K, Sabin I: Lemierre’s syndrome an unusual manifestation of spinal infection. J Bone Joint Surg, Br Vol 2006,88(2):261–262.CrossRef 4. Saed S, Zafar U, Johnson LB: Fusobacterium causing concomitant liver and brain abscesses. Infect Dis Clin Pract 2005,13(5):265–267.CrossRef 5. Karkos PD, Asrani S, Karkos CD, Leong SC, Theochari EG, Alexopoulou EG, Assimakopoulos AD: Lemierre’s

syndrome: a systematic review. Laryngoscope 2009,119(8):1552–1559.PubMedCrossRef 6. Kujur R, Rao SM, Badwaik G, Paraswani R: Thrombosis associated with right internal jugular central venous catheters: A prospective observational study Indian. J Crit Care Med 2012,16(1):17–21. 7. Van Rooden CJ, Tesselaar MET, Osanto S, Rosendaal FR, Huisman MV: Deep vein thrombosis associated with Central Venous Catheters; a review. J Thromb Haemost 2005, 3:2409–2419.CrossRef 8. Lordick F, Hentrich M, Decker T, Hennig M, Pohlman H, Hartenstein R, Peschel C: Ultrasound screening for internal jugular vein thrombosis aids the detection of central venous catheter-related infections in patients with haemato-oncological diseases: a prospective observational study. Br J Haematol 2003,120(6):1073–1078.PubMedCrossRef 9.

Comments are closed.