The aim of the study was to use non-invasive thoracic electrical bioimpedance (TEB) to evaluate hemodynamic modulators and subsequent hemodynamic status in uncontrolled hypertensive patients, receiving at least two antihypertensive drugs. A number of 134 uncontrolled hypertensive patients with essential hypertension were evaluated in nine European Hypertension Excellence centers by means of TEB (the HOTMAN (R) System). Baseline office systolic and diastolic BP averaged 156/92 mmHg. Hemodynamic measurements show that almost all patients (98.5%) presented at least one altered hemodynamic modulator: intravascular hypervolemia (96.4%) and/or hypoinotropy (42.5%) and/or
see more vasoconstriction (49.3%). Eleven combinations of hemodynamic modulators were present in the study population, the most common being concomitant hypervolemia, hypoinotropy and vasoconstriction in 51(38%) patients. Six different hemodynamic states (pairs of mean arterial pressure and stroke index) were found. Data suggest that there is a strong relation between hypertension and abnormal hemodynamic modulators. This method might be helpful for treatment individualization of hypertensive patients.”
“Aims To determine predictors of health care utilization in women
with urinary incontinence (UI) from the population to specialty care. Methods: The General Longitudinal Overactive Bladder Evaluation- UI is a population- based study on the natural history of UI in women >= 40 years of age. Prevalence of UI was estimated using SNX-5422 order the Bladder Health Survey (BHS). Survey data were linked with electronic health records (EHRs) to examine factors associated with a clinical UI diagnosis using logistic regression. Risk factors analyzed EVP4593 manufacturer included: UI symptoms, subtypes, bother, severity, duration, and effect on quality of life, and demographic and other health characteristics. All statistical tests were twosided with a P-value < 0.05 being significant. Results: The overall prevalence of any UI based on responses to the BHS was
1,618/4,064 (40%). Of the 1,618 women with UI, there were only 398 (25%) women with EHR (clinical) diagnosis of UI. Women with UI versus those without UI were more likely to be have a BMI > 25 kg/m(2) (70% vs. 58%), more likely to be parous (91% vs. 87%) and college educated (54% vs. 46%), P < 0.001. After adjusting for confounders in the model, variables significantly associated with clinical UI diagnosis included: older age (OR 1.96), higher parity (> 1 birth) (OR 1.76), higher urgency UI (OR 1.08), adaptive behavior (OR 1.2), and UI bother scores (OR 1.01), as well as more frequent outpatient visits (OR 1.03), P < 0.05. Conclusions: UI is a highly prevalent condition with only a minority of women seeking care.