total hip arthroplasty, revision total hip arthroplasty, knee arthroscopy, laminectomy, lumbar/thoracic arthrodesis,

and femoral fracture repair No other procedure group accounted for >2% of the adverse events

Conclusions: Only a few procedures account for the vast majority of adverse events in the first thirty days following orthopaedic surgery. Concentrating quality-improvement efforts on these procedures may be an effective AG-014699 molecular weight way for surgeons and other stakeholders to improve perioperative care and reduce costs in orthopaedic surgery.”
“BACKGROUND: Glycerol was used to produce efficient adsorbents with a high surface area for organic contaminants by a combined process based on polymerization, carbonization and activation.

RESULTS: Glycerol and sulfuric acid catalyst at concentrations of 0, 0.5, 1, 2 and 5 mol% were heated to 150 degrees C to form polyglycerol, which was then decomposed at 580 degrees C and activated with CO2 at 850 degrees C. The resulting activated carbons had a high specific area (1630 m2g-1) and high adsorption capacity of methylene blue used as a model organic contaminant. This process was also used to produce a special composite adsorbent based on expanded vermiculite (EV) coated with activated Ricolinostat purchase carbon. These composites were produced by impregnation of EV with glycerol followed by polymerization, thermal

decomposition and activation with CO2 to produce up to 25 wt% carbon and a surface area of 835 m2g-1.

CONCLUSIONS: The carbon layer present in the EV composite/activated carbon (GVE4CA2) produces a remarkable increase in the methylene blue adsorption capacity of the expanded vermiculite and strongly decreases undesirable Selleckchem Salubrinal water absorption. Copyright (c) 2012 Society of Chemical Industry”
“BACKGROUND: Lipopeptide production is strongly influenced by trace metals. The availability of free Fe2+ in the media throughout the process of fermentation was found to be very critical. Since free Fe2+ was reported to be sequestered by the lipopeptide as it was produced, intermittent feeding of Fe2+ was strategized and

optimized for enhanced lipopeptide production by marine Bacillus megaterium in glucose mineral salts medium (GMSM).

RESULTS: Studies with the single-dose Fe2+ (0.48 mmol L-1) supplementation after 8 h of fermentation resulted in lipopeptide concentration of 3.3 +/- 0.1 g L-1. Lipopeptide production was further enhanced to 4.2 +/- 0.15 g L-1 by adopting a multi-dose Fe2+ feeding strategy. The maximum product yield (YP/S) of 0.24 +/- 0.02 g g-1 with specific product formation rate (qp) of 0.124 +/- 0.01 g g-1 h-1 was achieved when 0.48 mmol L-1 Fe2+ was fed intermittently at different times as per the designed strategy.

CONCLUSION: Lipopeptide concentration was improved 4.7-fold by single-dosing and 5.8-fold by multiple dosing of Fe2+, when compared with GMSM without Fe2+ supplementation.

We illustrate the link from single unit activity to behavioral responses. The results suggest plausible neural mechanisms subserving the cognitive “”insight” capability originally attributed to rodents by Tolman & Honzik. Our time course analysis of neural responses shows how the interaction between hippocampus and PFC can yield the encoding of manifold information pertinent to spatial

planning, including prospective coding and Adavosertib distance-to-goal correlates.”
“Objective

To describe a biinstitutional experience with fine needle aspiration (FNA) of breast lesions occurring in men, over a period of over 10 years and to assess the role of FNA in detecting male breast cancer.

Study Design

Computer Patient records were searched from January 1990 to September 2007. HM781-36B in vivo Male patients who had a diagnosis of carcinoma on breast biopsy or resection were identified, and detailed chart review was done to assess demographics and correlate biopsy and FNA results.

Results

A total of 346,792 patients’ charts were searched, and 2.17 male patients were found to have had abreast mass and subsequent FNA. Combined in both institutions, FNA results were positive for carcinoma in 12 (5.5%) cases, negative in 181 (83.4%) cases, suspicions in 5 (2.3%) cases, indeterminate inconclusive in 3 (1.4%) cases and unsatisfactory in 16 (7.4%) cases. Matching biopsies

to confirm FNA results were available in 26 (12%) of the 217 cases. The calculated sensitivity and specificity for the malignant cases reached 100%. When suspicions cases were calculated for diagnostic accuracy, the sensitivity was 67% and the specificity 100%.

Conclusion

This RG-7112 cell line biinstitutional study demonstrates that FNA is a reliable but underutilized procedure

for the management of male breast lesions. (Acta Cytol 2009;53:369-374)”
“In this work, terahertz (THz) temperature-dependent properties of defect mode in a defective semiconductor-dielectric photonic crystal (SDPC) are theoretically investigated based on the calculated transmittance spectrum. Two different defective PCs, the symmetric structure of (Si/SiO2)(InSb)-In-N(SiO2/Si) (N) and the asymmetric one of (Si/SiO2)(InSb)-In-N(Si/SiO2)(N), will be considered. With a strongly temperature-dependent permittivity in defect layer InSb, the defect mode can be thermally tuned, that is, the defect frequency will be shifted to higher frequency as the temperature increases. With the inherent loss in InSb, the strength of defect mode will be strongly depressed at a higher temperature. We use the condition of impedance match to explain the presence of defect mode. The understanding of properties of defect mode could be of technical use in the terahertz optoelectronic applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3660230]“
“Background: Chronic wounds are both time consuming as well as costly.

“
“Two novel flavonoid glycosides, 6”’-dihydrophaseoylspinosin (1) and 6 ”,6”’-diferuloylspinosin (2), were isolated from the MeOH extract of Semen Ziziphi Spinosae, together with six known flavonoids, isovitexin-2 ”-O-beta-(6-O-E-feruloyl) glucopyranoside (3), spinosin

(4), isospinosin (5), 6000-feruloylspinosin (6), swertisin (7), and isovitexin-2 ”-O-beta-D-glucopyranoside (8). The structures of 1 and 2 were elucidated by spectroscopic methods including UV, IR, ESI-TOF-MS, 1D NMR, and 2D NMR experiments.”
“Microbial transformation of 7,8-dimethoxyflavone (1) by Mucor ramannianus produced five metabolites: 7,8-dimethoxy-4′-hydroxyflavone (2), 3′,4′-dihydroxy-7,8-dimethoxyflavone (3), 7,3′-dihydroxy-8-methoxyflavone (4), 7,4′-dihydroxy-8-methoxyflavone SN-38 clinical trial (5) and 8-methoxy-7,3′,4′-trihydroxyflavone (6). It was, however, completely converted to a single metabolite, 7-hydroxy-8-methoxyflavone (7) by Aspergillus flavus. 5-Methoxyflavone (8), when fermented with Beauveria bassiana, gave a single product, GW4869 concentration 5-methoxyflavanone (9). Conversion of 8 with Aspergillus alliaceus yielded the metabolite 4′-hydroxy-5-methoxyflavone (10). The structures of the compounds 2-7, 9 and 10 were established by spectroscopic

methods.”
“We clarified the impact of omentectomy for advanced gastric cancer on patient survival from the surgical results of a high-volume center in Japan.

Patients who received curative gastrectomy were divided into two groups based on whether they underwent omentectomy. The propensity score-matching method was used to assemble a well-balanced cohort, and relapse-free SRT2104 inhibitor survival and the pattern of recurrence were compared.

For this study, 330 patients who fulfilled the inclusion criteria participated and were divided into two groups: group

R, patients who received omentectomy, and group P, patients who received omentum-preserving gastrectomy. After performing score-matching, 196 patients were selected. The 3- and 5-year relapse-free survival rates were 72.9 % (95 % confidence interval, 64.1-81.7) and 66.2 % (56.6-75.8 %) in group R, and 76.7 % (67.9-81.2) and 67.3 % (55.1-79.5) in group P, which were not significantly different (P = 0.750). Regarding sites of relapses, no differences were observed between the groups (P = 0.863).

In this series, omentum-preserving gastrectomy for advanced gastric cancer did not increase the peritoneal relapse rate or affect patient survival compared to conventional gastrectomy. The non-inferiority of the omission of omentectomy should be evaluated by a randomized controlled trial.

Methods: Clinical and microbiologic data were collected prospectively from 444 consecutive patients presenting with an Fludarabine cost influenza-like illness (ILI) to a large pediatric hospital at the beginning of the S-OIV outbreak in Australia.

Results:

Of 444 patients, 119 had polymerase chain reaction-confirmed S-OIV. Influenza A virus was detected by direct immunofluorescence in only 69 of these. Overall, inadequate respiratory samples were more common with rayon than flocked swabs (P = 0.01). The mean age of patients with S-OIV was higher than those with another cause of an ILI (10.2 vs. 6.4 years; P < 0.0001). The commonest symptoms in S-OIV were fever (93%) and cough (92%), followed by coryza (78%), sore throat (72%), headache (59%), myalgia (49%), vomiting (23%), and

diarrhea (16%). Clinical features did not discriminate between patients with S-OIV and those with another ILI, except headache and myalgia, which were more common in children younger than 5 years who had S-OIV than those who did not (headache: P < 0.0001; myalgia: P = 0.0004). More patients with S-OIV had contact with a confirmed case but contact history had insufficient positive predictive value (44%) and negative predictive value (78%) for identifying S-OIV. Only 2% of the patients had a history of travel, and only 1 of these had S-OIV.

Conclusions: SHP099 A clinical case definition Torin 1 clinical trial is unlikely to be useful for discriminating patients with S-OIV from those with another cause of an ILI during winter. Direct immunofluorescence for influenza A cannot be used alone to reliably detect S-OIV.”
“We demonstrate results of a numerical analysis on functionality of waveguide circulators working in the

spectral range of optical communication. Studied circulators were silicon-based three-port waveguide splitters where working elements were slabs of two-dimensional magnetophotonic crystals (2D MPCs) with different structural parameters. An optimized circulator had a 2D MPC slab-hexagonal array of cylindrical air holes in silicon with a magneto-optical defect made of bismuth-substituted yttrium iron garnet and demonstrated an insertion loss of 9 dB and an isolation of 16 dB. If compared to circulators reported in Z. Wan and S. Fan [Appl. Phys. B 81, 369 (2005)], the studied circulators are attractive for realization due to the relative simplicity of their designs. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3562043]“
“The usefulness of reverse transcription loop-mediated isothermal amplification (RT-LAMP) for the rapid diagnosis of hepatitis C virus (HCV) RNA was evaluated. This assay showed higher sensitivities than that of nested RT-PCR, with a detection limit of 600 IUmL(-1), and no cross-reactivity was observed with hepatitis A virus, hepatitis B virus and hepatitis E virus.

Of 620 dogs with intact deep nociception before surgery, 606 (97.7%) were ambulatory after surgery. Despite maintaining the ability to walk, 7 dogs were judged to have an unsuccessful outcome because the severity of ataxia did not improve. Of 211 paraplegic dogs with loss of deep nociception, 110 (52.1%) dogs became ambulatory after surgery. Long-term complications included

incontinence, permanent neurologic deterioration, GSK3235025 in vivo and self-mutilation. Dogs with paraplegia before surgery had a higher frequency of urinary or fecal incontinence, compared with dogs that were ambulatory.

Conclusions and Clinical Relevance-Prognosis for dogs with thoracolumbar IVDH that retain deep nociception in at least 1 of the pelvic limbs or tail before surgery was good. AC220 research buy (J Am Vet Med Assoc 2012;241:1617-1626)”
“The development and implementation of programs in the U.S. to minimize risks and assess unintended consequences of new medications has been increasingly required by the Food and Drug Administration (FDA) since the mid 1990s. This paper provides fourcase histories of risk management and post-marketing surveillance programs utilized recently to address problems associated with possible abuse, dependence and diversion. The pharmaceutical sponsors of each of these drugs were invited

to present their programs and followed a similar template for their summaries that are included in this article. The drugs and presenting companies were OxyContin (R), an analgesic marketed

by Purdue Pharma L.P., Daytrana (R) and Vyvanse (R), ADHD medications marketed by Shire Pharmaceuticals, Xyrem (R) for narcolepsy marketed by Jazz Pharmaceuticals, FK866 molecular weight and Subutex (R) and Suboxone (R) for opioid dependence marketed by Reckitt Benckiser Pharmaceuticals Inc. These case histories and subsequent discussions provide invaluable real-world examples and illustrate both the promise of risk management programs in providing a path to market and/or for keeping on the market drugs with serious potential risks. They also illustrate the limitations of such programs in actually controlling unintended consequences, as well as the challenge of finding the right balance of reducing risks without posing undue barriers to patient access. These experiences are highly relevant as the FDA increasingly requires pharmaceutical sponsors to develop and implement the more formalized and enforceable versions of the risk management term Risk Evaluation and Mitigation Strategies (REMS). (C) 2009 Elsevier Ireland Ltd. All rights reserved.”
“Local anesthetics effectively block and relieve pain, but with a relatively short duration of action, limiting its analgesic effectiveness. Therefore, a long-acting local anesthetic would improve the management of pain, but no such agent is yet available for clinical use.

Associations were assessed using propensity score methods.

Results: Included were 8316 patients with complete data, of whom 214 (2.6%) had hypothermia induced and 2521 (30%) survived to discharge. Of patients reported to receive hypothermia, only 40% were documented as achieving

a temperature between 32 degrees C selleck inhibitor and 34 degrees C. Adjusted for known potential confounders using propensity score methods, induced hypothermia was associated with an odds ratio of survival of 0.90 (95% confidence interval: 0.65, 1.23; p-value = 0.49) compared to no hypothermia. Induced hypothermia was associated with an odds ratio of neurologically-favorable survival of 0.93 (95% confidence interval: 0.65, 1.32; p-value = 0.68) compared to no hypothermia. For patients with shockable first-recorded rhythm, induced hypothermia was associated with an odds ratio of survival of 1.43 (95% confidence interval: 0.68, 3.01; p-value = 0.35) compared to no hypothermia.

Conclusion: Hypothermia is induced infrequently in patients resuscitated from in-hospital cardiac arrest with

only 40% achieving target temperatures. Induced hypothermia was not associated with improved or worsened survival or neurologically-favorable survival. The lack of benefit in this population may reflect lack of effect, inefficient application of the intervention, or residual confounding. High-quality buy Napabucasin controlled studies are required to better characterize the effect of induced hypothermia in this population.

(C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“OBJECTIVES: To estimate, from the literature, when nonlactating postpartum women regain fertility.

DATA selleck kinase inhibitor SOURCES: We searched PubMed and Cochrane Library databases for all articles (in all languages) published in peer-reviewed journals from database inception through May 2010 for evidence related to the return of ovulation and menses in nonlactating postpartum women. Search terms included “”Fertility”" (Mesh) OR “”Ovulation”" (Mesh) OR “”Ovulation Detection”" (Mesh) OR “”Ovulation Prediction”" (Mesh) OR fertility OR ovulat* AND “”Postpartum Period”" (Mesh) OR postpartum OR puerperium AND Human AND Female.

METHODS OF STUDY SELECTION: We included articles assessing nonlactating women’s first ovulation postpartum. Studies in which women breastfed for any period of time or in whom lactation was suppressed with medications were excluded.

TABULATION, INTEGRATION AND RESULTS: We identified 1,623 articles; six articles reported four studies met our inclusion criteria. In three studies utilizing urinary pregnanediol levels to measure ovulation, mean day of first ovulation ranged from 45 to 94 days postpartum; 20%-71% of first menses were preceded by ovulation and 0%-60% of these ovulations were potentially fertile.

The wiring diagram reported here can help in understanding the mechanistic basis https://www.selleckchem.com/products/jnk-in-8.html of behavior by generating predictions about future experiments involving genetic perturbations,

laser ablations, or monitoring propagation of neuronal activity in response to stimulation.”
“We demonstrate the isolation of two free carrier scattering mechanisms as a function of radial band bending in InN nanowires via universal mobility analysis, where effective carrier mobility is measured as a function of effective electric field in a nanowire field-effect transistor. Our results show that Coulomb scattering limits effective mobility at most effective fields, while surface roughness scattering only limits mobility under very high internal electric fields. High-energy a particle irradiation is used to vary the ionized donor concentration, and the observed decrease in mobility and increase in donor concentration are compared to Hall effect results of high-quality InN thin films. Our results show that for

nanowires with relatively high doping and large diameters, controlling Coulomb scattering from ionized dopants should be given precedence over surface engineering when seeking to maximize nanowire Selleckchem WH-4-023 mobility. (C) 2011 American Institute of Physics. [doi:10.1063/1.3611032]“
“It is essential to isolate high-quality DNA from muscle tissue for PCR- based applications in traceability of animal origin. We wished to examine the impact of cooking meat to a range of core temperatures on the quality and quantity of subsequently

isolated genomic (specifically, nuclear) DNA. Triplicate steak samples were cooked in a water bath (100 degrees C) until their final internal temperature was 75, 80, 85, 90, 95, or 100 degrees C, and DNA was extracted. Deoxyribonucleic acid quantity was significantly reduced in cooked meat samples compared with raw (6.5 vs. 56.6 ng/mu L; P < 0.001), but there was no relationship with cooking temperature. Quality (A(260)/A(280), i. e., absorbance at 260 and 280 nm) was also affected by cooking (P < 0.001). For all 3 genes, large PCR amplicons ( product size > 800 bp) were observed only when using DNA from raw meat and steak cooked to lower core temperatures. Small amplicons (< 200 bp) Selleck BI-D1870 were present for all core temperatures. Cooking meat to high temperatures thus resulted in a reduced overall yield and probable fragmentation of DNA to sizes less than 800 bp. Although nuclear DNA is preferable to mitochondrial DNA for food authentication, it is less abundant, and results suggest that analyses should be designed to use small amplicon sizes for meat cooked to high core temperatures.”
“CYP2E1, as a member of the cytochrome P450s (CYPs) super-family, is in charge of six percent drug metabolism involving a diversity of drugs distinct in structures and chemical properties, such as alcohols, monocyclic compounds (e. g.

More investigation is required to prove a possible correlation between existing HLA-B27 and the propensity to develop this clinical problem. (C) 2013 Elsevier Ireland Ltd. All rights

reserved.”
“Background: Muscular instability is an important risk factor for lumbar spine injury and chronic low-back pain. Although the lumbar multifidus muscle is considered an important paraspinal muscle, its design features are not completely understood. The purpose of the present study was to determine the architectural properties, in vivo sarcomere length operating range, this website and passive mechanical properties of the human multifidus muscle. We hypothesized that its architecture would be characterized by short fibers and a large physiological cross-sectional area and that it would operate over a relatively wide range of sarcomere lengths but would have very stiff passive material properties.

Methods: Protein Tyrosine Kinase inhibitor The lumbar spines of eight cadaver specimens were excised en bloc from T12 to the sacrum. Multifidus muscles were isolated from each vertebral level, permitting the architectural measurements of mass, sarcomere length, normalized fiber length, physiological cross-sectional area,

and fiber length-to-muscle length ratio. To determine the sarcomere length operating range of the muscle, sarcomere lengths were measured from intraoperative biopsy specimens that were obtained with the spine in the flexed and extended positions. Galardin The material properties of single muscle fibers were obtained from passive stress-strain tests of excised biopsy specimens.

Results: The average muscle mass (and standard error) was 146 +/- 8.7 g, and the average sarcomere length was 2.27 +/- 0.06 mu m, yielding an average normalized fiber length of 5.66 +/- 0.65 cm, an average physiological cross-sectional area of 23.9 +/- 3.0 cm(2), and an average fiber length-to-muscle length ratio of 0.21 +/- 0.03. Intraoperative sarcomere length measurements revealed that the muscle operates from

1.98 +/- 0.15 mu m in extension to 2.70 +/- 0.11 mu m in flexion. Passive mechanical data suggested that the material properties of the muscle are comparable with those of muscles of the arm or leg.

Conclusions: The architectural design (a high cross-sectional area and a low fiber length-to-muscle length ratio) demonstrates that the multifidus muscle is uniquely designed as a stabilizer to produce large forces. Furthermore, multifidus sarcomeres are positioned on the ascending portion of the length-tension curve, allowing the muscle to become stronger as the spine assumes a forward-leaning posture.”
“Primary aldosteronism (PA) is an important cause of secondary hypertension, is being increasingly diagnosed and may account for more than 10% of hypertensive patients, both in primary care and in referral centers.

38) or mean change in intraocular pressure (IOP) (mean decrease 2.6 mm Hg +/- 1.5 [SD] and 1.6 +/- 0.5 mm Hg, respectively) (P = .47).

CONCLUSION: Despite the need for vitrectomy and the attendant increased demands in postoperative care, both the vitrectomy group and no-vitrectomy group had improved logMAR CDVA and IOP.”
“BACKGROUND: The 6-minute walk test is widely used to characterize

activity tolerance and response to therapy in pulmonary arterial hypertension (PAH) but provides little information about cardiopulmonary pathophysiology. The aim of the present study was to determine whether measures of pulmonary gas exchange during relatively light exercise could differentiate between PAH patients and healthy individuals and also stratify disease severity.

METHODS: The study comprised 40 PAH patients and 25 matched controls. Napabucasin solubility dmso Each completed a sub-maximal exercise test, consisting of 2 minutes of rest, 3 minutes of exercise, and 1 minute of recovery. Ventilation, pulmonary gas exchange, arterial oxygen saturation (Sao(2)), and heart rate were measured throughout using a simplified gas analysis system.

RESULTS: A number of gas exchange variables differentiated PAH patients

and controls. End-tidal CO(2) (P(ET)CO(2)) and Sao(2), were lower in PAH vs controls (31 +/- 7 vs 39 +/- 3 mm Hg and 89% +/- 5% vs 95% +/- 2%, respectively, p < 0.05). Breathing efficiency (V(E)/VCO(2) ratio) was poorer in PAH vs controls (42 +/- 10 vs 33 +/- 5, p < 0.05).-In addition, find protocol P(ET)CO(2) and V(E)/VCO(2) discriminated between different severities of PAH.

CONCLUSIONS: Gas exchange variables obtained during light sub-maximal exercise differentiated PAH patients from healthy controls and also between different severities

of PAH. Sub-maximal exercise gas exchange may be a useful end point measure in a PAH population. J Heart Lung Transplant 2011;30:1133-42 (C) 2011 International Society for Heart and Lung Transplantation. All rights reserved.”
“The series selleck compound of V spinels [A(2+)] V-2 O-4 (A = Cd, Mn, Zn, Mg) provides an opportunity to tune the V-V distance continuously, in the frustrated pyrochlore lattice of the spinel. This system has been shown to approach the metallic state when V-V distance is reduced. The proximity to the transition leads to a dimerized structure in ZnV2 O-4 caused by lattice instabilities. A different manner to tune the V – V distance of this structure is to fix the A(2+) cation (in our case, Zn) and apply pressure. We have analyzed the evolution of the electronic structure of the system in the dimerized state. Such structure prevents the system to present a metallic phase at moderate pressures. We have also calculated the transport properties in a semiclassical approach based on Boltzmann transport theory.

The size and number density of free volume domains in the PVP-PEG blends were determined as functions of blend composition and relative humidity of the surrounding atmosphere, which controls the amount of absorbed water. Correlating the free volume, adhesion behaviors, and tensile properties of the blends, the range of free volume favoring pressure-sensitive adhesion in examined compositions was established. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 2408-2421, 2011″
“The molecular dynamics simulation (MD) method has been widely applied to the investigation of the thermal conductivity SBE-β-CD mw of single crystalline materials during

last decade but no report on the thermal conductivity of polycrystalline solids by direct MD simulation with three-dimensional polycrystalline structure is found so far. In this paper, the periodic configuration of nanocrystalline argon for MD simulation is constructed based on the Voronoi tessellation method. The thermal conductivity of both perfect single crystal and nanocrystalline bulk argon are calculated by the

Green-Kubo method. The results are compared with experiments as well as MD simulation results reported by others. The thermal conductivity of nanocrystalline argon with the average grain size of 5 nm is much lower than that of the corresponding perfect single crystal at temperatures between 10 and 70 K. The reduction can be attributed to grain boundary thermal resistance Selleck TPCA-1 due to large number of grain interfaces in polycrystalline argon, as well as their

limitation on the phonon mean free path. The magnitude of estimated grain boundary thermal resistance at different temperatures is on the scale of 10(-9) m(2)K/W. The grain boundary thermal resistance is larger at lower temperature. This report demonstrates that the thermal property of Selleckchem DZNeP polycrystalline materials can be investigated by MD simulation. (C) 2010 American Institute of Physics. [doi:10.1063/1.3510523]“
“PURPOSE: To compare visual function after phacoemulsification with implantation of a multifocal intraocular lens (IOL) or a monofocal IOL.

SETTING: Department of Ophthalmology, Affiliated Hospital of Qingdao University Medical College, Qingdao, Shandong, China.

METHODS: This study comprised patients with unilateral cataract who had phacoemulsification with implantation of an AcrySof ReSTOR SA60D3 multifocal IOL (multifocal group) or an AcrySof SA60AT single-piece monofocal IOL (monofocal group). Postoperative visual function, including uncorrected (UDVA) and corrected (CDVA) distance visual acuity; uncorrected (UNVA), corrected (CNVA), and distance-corrected near visual acuity; and contrast sensitivity were evaluated 1 week, 1 month, and 6 months postoperatively. Patient-reported vision and spectacle independence in the 2 groups were also compared.